Sample size and power determination when limited preliminary information is available
نویسندگان
چکیده
منابع مشابه
Sample size and power determination when limited preliminary information is available
BACKGROUND We describe a novel strategy for power and sample size determination developed for studies utilizing investigational technologies with limited available preliminary data, specifically of imaging biomarkers. We evaluated diffuse optical spectroscopic imaging (DOSI), an experimental noninvasive imaging technique that may be capable of assessing changes in mammographic density. Because ...
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groups. From a review of the literature and from their own clinical experience, the investigators anticipate approximately 50% of the women with a regular training program will suffer an ACL tear. They hypothesize that a reduction by one-half, resulting in only a 25% incidence in ACL injuries in the hamstrings training group, would be a clinically significant finding. The investigators set their
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ژورنال
عنوان ژورنال: BMC Medical Research Methodology
سال: 2017
ISSN: 1471-2288
DOI: 10.1186/s12874-017-0329-1